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Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis

Received: 28 April 2021     Accepted: 17 May 2021     Published: 27 May 2021
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Abstract

Background: Diabetes mellitus has been shown to be an associated risk factor for peri-implantitis. Peri-implantitis has become the leading cause of implant failure. Objective: To ensure the postoperative efficacy of diabetic patients and avoid the occurrence of peri-implantitis, research progress on the mechanism and preventive measures of diabetes induced peri-implantitis were elaborated. Methods: With "diabetes mellitus or diabetes or DM, peri-implantitis, implant, osseointegration" as the search terms, related articles published during 2013-2021 in PubMed, CNKI, ScienceDirect and other databases were searched. Results: The changes in the type and proportion of bacteria around implants in diabetic patients break the balance between bacteria and host defense system. Diabetic patients with insulin resistance and persistent hyperglycemia inhibit osteoblast differentiation, induce osteoclast activation and make adverse effects on osseointegration. The immune inflammatory state and local microvascular lesions of the body slow down postoperative tissue healing and induce peri-implantitis. According to the relevant mechanisms, many experiments have achieved good results in reducing the incidence of peri-implantitis in patients with diabetes through plaque control, blood glucose management and implant interface improvement. Conclusion: Diabetic patients have a higher risk of peri-implantitis, so implant patients with diabetes mellitus should undertake related prevention and treatment to reduce the risk of peri-implantitis.

Published in International Journal of Dental Medicine (Volume 7, Issue 1)
DOI 10.11648/j.ijdm.20210701.12
Page(s) 10-14
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Diabetes Mellitus, Implant, Peri-Implantitis, Osseointegration

References
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Cite This Article
  • APA Style

    Wanyun Lin, Chen Xie, Chunyi Cao, Shengping Cao, Xiaoting Li, et al. (2021). Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. International Journal of Dental Medicine, 7(1), 10-14. https://doi.org/10.11648/j.ijdm.20210701.12

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    ACS Style

    Wanyun Lin; Chen Xie; Chunyi Cao; Shengping Cao; Xiaoting Li, et al. Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. Int. J. Dent. Med. 2021, 7(1), 10-14. doi: 10.11648/j.ijdm.20210701.12

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    AMA Style

    Wanyun Lin, Chen Xie, Chunyi Cao, Shengping Cao, Xiaoting Li, et al. Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis. Int J Dent Med. 2021;7(1):10-14. doi: 10.11648/j.ijdm.20210701.12

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  • @article{10.11648/j.ijdm.20210701.12,
      author = {Wanyun Lin and Chen Xie and Chunyi Cao and Shengping Cao and Xiaoting Li and Tingting Li and Yujia Zhai and Jingni Guo and Vannesa Bongani Muyeleka and Zhuling Guo},
      title = {Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis},
      journal = {International Journal of Dental Medicine},
      volume = {7},
      number = {1},
      pages = {10-14},
      doi = {10.11648/j.ijdm.20210701.12},
      url = {https://doi.org/10.11648/j.ijdm.20210701.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijdm.20210701.12},
      abstract = {Background: Diabetes mellitus has been shown to be an associated risk factor for peri-implantitis. Peri-implantitis has become the leading cause of implant failure. Objective: To ensure the postoperative efficacy of diabetic patients and avoid the occurrence of peri-implantitis, research progress on the mechanism and preventive measures of diabetes induced peri-implantitis were elaborated. Methods: With "diabetes mellitus or diabetes or DM, peri-implantitis, implant, osseointegration" as the search terms, related articles published during 2013-2021 in PubMed, CNKI, ScienceDirect and other databases were searched. Results: The changes in the type and proportion of bacteria around implants in diabetic patients break the balance between bacteria and host defense system. Diabetic patients with insulin resistance and persistent hyperglycemia inhibit osteoblast differentiation, induce osteoclast activation and make adverse effects on osseointegration. The immune inflammatory state and local microvascular lesions of the body slow down postoperative tissue healing and induce peri-implantitis. According to the relevant mechanisms, many experiments have achieved good results in reducing the incidence of peri-implantitis in patients with diabetes through plaque control, blood glucose management and implant interface improvement. Conclusion: Diabetic patients have a higher risk of peri-implantitis, so implant patients with diabetes mellitus should undertake related prevention and treatment to reduce the risk of peri-implantitis.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Research Progress on the Mechanism and Preventive Measures of Diabetes Induced Peri-implantitis
    AU  - Wanyun Lin
    AU  - Chen Xie
    AU  - Chunyi Cao
    AU  - Shengping Cao
    AU  - Xiaoting Li
    AU  - Tingting Li
    AU  - Yujia Zhai
    AU  - Jingni Guo
    AU  - Vannesa Bongani Muyeleka
    AU  - Zhuling Guo
    Y1  - 2021/05/27
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ijdm.20210701.12
    DO  - 10.11648/j.ijdm.20210701.12
    T2  - International Journal of Dental Medicine
    JF  - International Journal of Dental Medicine
    JO  - International Journal of Dental Medicine
    SP  - 10
    EP  - 14
    PB  - Science Publishing Group
    SN  - 2472-1387
    UR  - https://doi.org/10.11648/j.ijdm.20210701.12
    AB  - Background: Diabetes mellitus has been shown to be an associated risk factor for peri-implantitis. Peri-implantitis has become the leading cause of implant failure. Objective: To ensure the postoperative efficacy of diabetic patients and avoid the occurrence of peri-implantitis, research progress on the mechanism and preventive measures of diabetes induced peri-implantitis were elaborated. Methods: With "diabetes mellitus or diabetes or DM, peri-implantitis, implant, osseointegration" as the search terms, related articles published during 2013-2021 in PubMed, CNKI, ScienceDirect and other databases were searched. Results: The changes in the type and proportion of bacteria around implants in diabetic patients break the balance between bacteria and host defense system. Diabetic patients with insulin resistance and persistent hyperglycemia inhibit osteoblast differentiation, induce osteoclast activation and make adverse effects on osseointegration. The immune inflammatory state and local microvascular lesions of the body slow down postoperative tissue healing and induce peri-implantitis. According to the relevant mechanisms, many experiments have achieved good results in reducing the incidence of peri-implantitis in patients with diabetes through plaque control, blood glucose management and implant interface improvement. Conclusion: Diabetic patients have a higher risk of peri-implantitis, so implant patients with diabetes mellitus should undertake related prevention and treatment to reduce the risk of peri-implantitis.
    VL  - 7
    IS  - 1
    ER  - 

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Author Information
  • School of Dentistry, Hainan Medical University, Haikou, PR China

  • School of Dentistry, Hainan Medical University, Haikou, PR China

  • 2Hainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, PR China

  • School of Clinical Medicine, Hainan Medical University, Haikou, PR China

  • Department of Dentistry, the First Affiliated Hospital of Hainan Medical University, Haikou, PR China

  • School of Clinical Medicine, Hainan Medical University, Haikou, PR China

  • School of Clinical Medicine, Hainan Medical University, Haikou, PR China

  • School of Dentistry, Hainan Medical University, Haikou, PR China

  • School of Clinical Medicine, Hainan Medical University, Haikou, PR China

  • School of Dentistry, Hainan Medical University, Haikou, PR China

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